33 min via Expreso Manuel Rivera Morales/PR-181 Fastest route now, avoids slowdown on PR-26 San Juan Get on Hwy 1 S/PR-1 S in Santurce from PR-26 4 min Continue on Hwy 1 S/PR-1 S. Take Expreso Las Américas/PR-18 and Av. Jesús T. Piñero/PR-17 to Expreso Manuel Rivera Morales/Expreso Trujillo Alto/PR-181 in Río Piedras. Take the PR-181 exit from Av. Jesús T. Piñero/PR-17 10 min Continue on Expreso Manuel Rivera Morales/PR-181. Drive to Calle 6 in Trujillo Alto 13 min Trujillo Alto