Via Autop. José de Diego/PR-22 W Fastest route now due to traffic conditions This route has tolls. San Juan Get on Hwy 1 S/PR-1 S in Santurce from PR-26 Take Autop. José de Diego/PR-22 W to Hwy 160/PR-160 in Vega Baja. Take the Route 160 exit from Autop. José de Diego/PR-22 W Continue on Hwy 160/PR-160 to your destination in Miranda Vega Baja