via Expreso Román Baldorioty de Castro/PR-26 Best route now due to traffic conditions This route has tolls. San Juan Puerto Rico Take C. de la Luna and PR-25 to Expreso Román Baldorioty de Castro/PR-26 in Santurce Continue on Expreso Román Baldorioty de Castro/PR-26. Take Av. Jesús T. Piñero/PR-17 to Expreso Manuel Rivera Morales/Expreso Trujillo Alto/PR-181 in Río Piedras. Take the Puerto Rico 181 exit from Av. Jesús T. Piñero/PR-17 Continue on Expreso Manuel Rivera Morales/Expreso Trujillo Alto/PR-181. Take C. De Diego/PR-47 and Av. 65 de Infantería/PR-3 S to C. 16 in Sabana Llana Sur, San Juan, Puerto Rico C. 16